Effect of Leuprolide formulations on regulatory management practices in metastatic prostate cancer

Effect of Leuprolide formulations on regulatory management practices in metastatic prostate cancer

In this accompanying article, Brenda Heath, RN, discusses the main challenges related to the use of leuprolide acetate and leuprolide mesylate from an organizational management perspective.

In this new Medical Perspectives for Urology series, “Expert views on advanced/metastatic prostate cancerThought leaders in the management of hormone-sensitive or castration-resistant prostate cancer reflect developments in the treatment landscape, including key considerations in the use of different formulations of leuprolide. Given the challenges in using leuprolide formulations from a regulatory management perspective, Brenda Heath, RN, discusses the points Major related to nurse training, inventory management practices, and patient assistance programs at the upcoming accompanying interview.

Urology times®:Does the nursing staff need special training on how to prepare and administer leuprolide?

heat: We always have a training method prepared for … our new nurses, and they follow experienced nurses who have injected this drug multiple times. Usually, the training is combined with an experienced nurse training the new nurse, observing at first and then getting their hands on it. Most nurses… [have] expertise [and] Learn how to administer a subcutaneous injection. Most of the training comes from simply being able to appropriately mix different leuprolide acetate medications and [knowing] how to manage [them]. However, … there is training available with both sponsors to help, [if needed]And the teacher’s nurse [can] Come… and help with that.

Urology times®: Are there any challenges to administering Leuprolide or other prostate cancer treatment stock?

heat: There were definitely more challenges [related to] Trying to keep any healthcare supplies in stock now…since COVID-19 (coronavirus disease 2019) [pandemic] He hits. But for the most part, I don’t think we had any limitations in terms of keeping it on hand or following it. We have a system in place [in which] We make sure we check out all of our medications whenever an injection is removed so we keep track of our inventory, reorder and resupply when that runs low.

Urology times®: Can you talk in more detail about the software and materials available from leuprolide manufacturers to help you with management and/or inventory challenges, such as product specific training materials and instructions or inventory management software?

heat: Most leuprolide injectables have inventory software that can help scan and ensure on-site inventory is up-to-date, and they can work automatically as the site restocks the product. That could come in handy. There are also great resources on each of the different drug websites that show how to mix and administer each of the injectables. can [be] Also useful. We also know that of course we have representatives who come to the site and are readily available with their information to support us if we have any questions. there [are] Support programs for most of these injections that can work to help patients who … have any financial problems. I’ve tried and worked with some support programs to help our patients who can’t afford medication.

Version has been edited for clarity.