Newly funded projects are racing to discover o

Brain Health Center® I am pleased to announce three rapid-launch research initiatives that seek to promote the development of the first objective measures of improved brain systems in response to interventions. The projects, funded with a transformative investment from Sammons Enterprises, will leverage massive individual brain data from BrainHealth . Project To identify changes in brain physiology, structure, and function associated with gains in overall psychosocial measures over time.

Currently, brain assessments focus only on early detection of brain deterioration or damage. Now is the time to turn this outdated approach and look for ways to measure brain improvement. Scientists at the Center for BrainHealth strive to discover signs of brain improvement in response to brain health training, lifestyle habits, and treatment regimens. The BrainHealth project provides rich and valuable data that allows us to do this – not only to address whether individuals can maintain brain health or prevent deterioration, but also to see if they can take steps and show measurable improvement in the brain over time,” said Sandra Bond Chapman, Ph.D., director of the Center for Brain Health and Dee Wiley Distinguished Professor, School of Behavioral and Brain Sciences at the University of Texas at Dallas.

The first project , Validation and identification of biomarkers experimentally (VIBE), It will use neuroimaging data from the BrainHealth Project to gain insight into how brain blood flow and connectivity change when an individual participates in brain health training and demonstrate gains on the BrainHealth Composite Index. These physiological features will, in turn, be used to validate the structure brain health index (BHI), an assessment of overall brain performance measured against a comprehensive set of scientifically robust measures of cognitive, emotional, social, and pragmatic functions. The team of researchers includes biostatistics director Jeff Spence, PhD, computational neuroscientist Munro Turner, PhD, professor and Meadows Foundation Chair in Behavioral and Brain Sciences Bart Ripma, PhD, and research scientist Sergey Chishkov, PhD.

The second project , linking functional and structural neuroimaging markers to brain health, It uses a different machine learning approach to big data analytics to identify differences in brain connectivity as brain health improves. Vince Calhoun, Ph.D., Jane and Budd Smith Chair, and Jeff Spence will use functional magnetic resonance imaging (fMRI) and sMRI data to identify aspects of the brain’s neural activity that predict response to interventions, and to validate behaviors. Measuring brain health with brain changes and evaluating a big data approach to further improve BHI using neuroimaging data.

third project, Collaborative data sharing dashboard, seeks to create a structure and system for securely sharing data from the BrainHealth Project platform with other researchers. The team includes Aaron Tate, Director of Emerging Technology, Laurie Cook, PhD, CCC-SLP, Director of Clinical Research, Julie Fratantoni, PhD, CCC-SLP, Chief Operating Officer of the BrainHealth Project, and Zhengsi Chang, data analyst. The researchers’ goal is to create an accessible application portal to advance the research objectives related to the project, foster more productive collaboration and attract new researchers to the platform. This opportunity to make rich, protected data available to researchers everywhere will help address an infinite number of brain health questions.

In the long term, these projects will contribute to the development of predictive models for early detection, interception and prevention of cognitive decline at the earliest using machine learning and artificial intelligence (AI). “This work is life-changing. For the first time, we’re looking beyond reactive measures and proactively thinking about ways to improve and raise brain health starting from a young age,” Chapman said. “We want to help people make positive changes in their brains and redefine what it means to thrive as individuals, society and society.”

The Scientific Review Committee consisted of three distinguished reviewers: Dr. Dr. Mark D’Esposito, Distinguished Brain Health Scientist at the BrainHealth Project; and Dr. Ian Robertson, Distinguished Chair at T-Bone Pickens and Co-Chair of the BrainHealth Project. The committee will meet on a regular basis to ensure rapid progress and achievement, and these projects have been undertaken by Sammons Enterprises, which recently gave BrainHealth the largest single corporate gift in its history and began the public phase of its work. Unlimited BrainHealth Comprehensive Campaign Another method for this transformative investment is to turbocharge the center’s ability to pioneer, test, and deliver new metrics that assess gains in brain health and performance. More rapid launch projects will be funded next year.

About the BrainHealth . projectThe BrainHealth . Project It is a landmark endeavor to promote proactive, preventative, and accurate brain health. This scientifically backed toolkit teaches everyday people how to build brain fitness through online brain health workouts along with live virtual coaching. It features the world’s first multidimensional measure of brain performance, the Brain Health Index. The software is delivered through an award-winning, easy-to-use, machine-learning-powered online platform. In addition to being a long-term, scalable program for people to maximize their brain fitness, it is also a powerful research platform for cognitive neuroscientists at the Center for Brain Health and collaborators around the world.

About the Brain Health Center®Brain Health Center® is a transitional research institute committed to promoting, maintaining, and restoring brain health throughout the lifespan. Key areas of research include the use of functional and structural neuroimaging techniques to better understand the neurobiology that underpins cognition and emotion in health and disease. This groundbreaking scientific exploration is quickly translated into practical innovations to improve the way people think, work and live, empowering people of all ages to unlock the potential of their minds. Transformational innovations rely on advanced heuristics tactics for strategic memory (Clever™), a proprietary methodology developed and tested by BrainHealth researchers and other teams over three decades.


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