Study identifies a candidate probiotic derived from tapioca for oral health

Researchers isolated LAB . strains Lactobacillus brevisAnd the Lactobacillus plantsFor therapeutic activity against oral pathogens Porphyromonas gingivalis (P. gingivalis), It is considered the backbone of periodontal diseaseAnd the Decreases in biofilm formation were observed after dental treatment. The pathogen is known to stimulate the production of biofilms implicated in the development of the disease.

“The ability of LAB CFS to disrupt biofilm formation activity at various concentrations is critical to preventing recolonization s. gums As the protective biofilm layer in the pocket is destroyed by the treatment,” Study authors write Oral biology.

to. short And the to. the plants Showed excellent antimicrobial and anti-biofilm activityP. gingivalis. “

Shift in the microbial balance

Periodontal disease is a chronic dental problem that affects nearly 50% of adults and adolescents in developing countries and P. gumsIt is one of the major microbes associated with disease pathogenesis and possesses a number of virulent factors, such as lipopolysaccharide (LPS) layer in cell walls, inactivation of adhesion, biofilm formation, and genipins for tissue degradation.

s. gums It is the primary pathogen that alters the balance of the oral microbiota and ultimately disrupts the regulation of the immune response pathway. Transformation in the oral microbiota leads to dysbacteriosis after invasion s. gums. “

Antibiotics and antibacterial mouthwash are recommended to prevent colonization after dental treatment, but the biofilm caused by P. gumsThe effectiveness of both antibiotics and mouthwash reduces tooth stains and reduces palate sensitivity.